http://www.retail.ua
mega-turnik.com.ua/

The Diabetes Drug Avandia and Heart Problems

In May 2007, the New England Journal of Medicine published an article citing that patients using the diabetes drug Avandia (rosiglitazone maleate) face an increased risk of Avandia side effects such as heart attack or heart-related death.This is especially troubling news for diabetics, who are already at an increased risk of heart attack.In addition, the ADOPT study (released in late June 2007) showed that women who take Avandia are at an increased risk of suffering bone fractures.

Avandia received Food and Drug Administration approval in June 1999 as a treatment for type 2 diabetes.

Fluid retention, bad cholesterol—and more

Although there was evidence that Avandia could cause fluid retention and a rise in “bad” cholesterol—two risk factors for heart problems—the FDA allowed Avandia to be marketed and sold, despite getting just a six-month review.

Doctors have written about 60 million Avandia prescriptions since GlaxoSmithKline put it on the market, including more than 13 million last year.

The authors of the NEJM article pooled the records of 28,000 patients involved in 42 clinical trials for Avandia. Patients taking Avandia were 64% more likely to die from heart problems and 43% more likely to suffer a heart attack than patients who were given another drug or a placebo.

In total, 158 patients involved in the Avandia clinical trials suffered a heart attack, and 61 people taking Avandia died.

Because most of the studies analyzed lasted only a few weeks, the risk of Avandia side effects may be much higher, according to Dr. Steven Nissen of the Cleveland Clinic, lead author of the NEJM study.

The FDA’s response

Based on the research of Dr. Nissen and his colleagues, the FDA has announced plans to conduct a more detailed examination of Avandia side effects.

Within two weeks of the publication of Dr. Nissen’s research, the agency ordered a “black-box” warning for Avandia’s label.

The agency is urging patients to speak with their doctors about other options for treating their diabetes symptoms, but it currently has no plans to issue an Avandia recall. That may change as the number of Avandia lawsuits grows.

Site Map • Privacy Statement • Disclaimer • Resources
© 2006 – All Rights Reserved

Sponsored by Hissey Kientz, LLP (Austin, TX)
Call toll-free for a free consultation: (866) 275-4454

The Hissey Kientz, LLP attorneys handle lawsuits, claims and settlements in Alabama, Alaska, Arizona, Arkansas, California,       Colorado, Connecticut, D.C., Delaware, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, KentuckyLouisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin and Wyoming.

Read More

The Laws of Life

The Mystery of Life’s Purpose

At some point in each individual’s life on Earth they undoubtedly and eventually come around to question their purpose for existing. The basis of this profound question usually begins with thoughts centered around- the reason why am I here, and my purpose in what appears as an experiential journey through this mystery we call life. Many of us have experienced these seemingly bizarre moments of life in which we find ourselves reaching for answers to help solidify our existence permitting us to feel as though we are not building our lives on sifting sand. Although these moments in life allow for a conscious awakening that demands our attention, they are often masked or shrouded throughout our lives as momentous events.

It does not always happen this way because many apparently mundane moments within our lives carry the seed of questions yet unanswered- and if we look closely, profound answers are lovingly contained in those special moments of time. Having exposed in a previous article, Timewave Zero the premise that our universe and all within it is being sourced continuously from the same fountain of life through cycles, it surely makes plausible sense to conclude certain natural laws of life govern our existence and could very well offer solace in a turbulent sea of life’s questions. It is through the proper understanding and personal application of these “Laws of Life” that enable us to live life fully in the moment appreciating the journey of life right where we find ourselves at any given moment, in the Now. However, it must be added, we still live in a delicate world that requires of us to plan for a future while co-existing in the moment.

Could these well defined universal Laws of Life help us better understand life’s mysteries while at the same time provide a solid foundation upon which we can receive direction and answers? In short, the answer is yes! By applying a level of understanding and reliance upon these laws of unwavering reliability we may soon find ourselves aligned with powerful forces which conspire to lift our lives higher up the ladder of joy. If we could accept that all possibilities exist in the present moment and remain focused in the Now of life, consciously allowing the Laws of Life to freely operate through us, we would soon recognize that we are in a co-created world which we have personal responsibility for bringing into existence. It is through these simple Laws that we are building a new Earth as we become receptive to our ultimate purpose for life itself. We are powerful co-creators and life is our school and playground too.

The Power of the Four Laws of Life

I would concede there are many Laws of Life; however in this post we will turn our focus only upon four important master laws that birth all the others. Given that all life within the universe of creation is encapsulated within the boundaries established by certain laws, some known and some of these we are just starting to unravel and comprehend.There are four basic, universal laws of utmost value for human life and these are the one we shall address.

It is through our understanding and application of the wisdom contained within these four Laws of Life that will determine our experiences we will entertain throughout or lives. During our lives many of our questions arise through the awareness of the very contrasts that exist having been created by the choices we made. Some of these experiences are on an individual basis while others can be experienced by the entirety of those on Earth.

Our collective (or individual) reaction to events which create our life experience are needed thus enabling us by way of contrast between various experiences to question what it is we then want to experience. Combine life’s cyclic movement and how we experience it with understanding the four Laws of Life- The Law of Love, The Law of Gratitude, The Law of Cause & Effect and The Law of Attraction you find many of life’s poised questions and formerly out-of-reach answers become vividly obvious.

Before we get into each of the Laws, it would be good to know that these laws are immutable and one cannot “break” them in the process of life here as we operate within the parameters of Free-Will. You may by choice either consciously or unconsciously turn against any of these fundamental Laws of Life and your life experience would reveal that something was “amiss”, essentially out of balanced alignment. If your course in life was not adjusted through the questioning/answer process we all go through, your subsequent experiences would become more amplified while the essence of your life experience would remain the same.

We have all heard the question phrased this way: “Why does this always happen to me?” Read on to discover the nature of these four Laws of Life and how to recognize their individual signatures in your life. Upon gaining a more thorough understanding of how they permeate all facets of our lives, we become internally empowered to co-create our own lives, and indeed our world at the same time through the infinite power residing in these Laws of Life.

 

Read More

Pirates, Piracy and the Law

The study of the history of Piracy and Pirates can be studied from the viewpoint of many vocations; including, technological, sociopolitical, or criminological. However piracy and pirates can also be look at through a legal perspective. The relevance of study piracy from the prism is best illustrated by consider what piracy and pirates are. Piracy was a crime, a violation of the law. Pirates are a class of criminals whose primary crime was piracy. As piracy is a crime their must be in existence specific laws on the subject. Like all criminal laws the laws regarding piracy serve to define what actions or combination of action or omissions would constitute piracy. Like all laws the laws relating to piracy have a source. The Source for laws includes custom, statue and treaties. The law also provides for finality. Laws sometimes have exceptions the exception to the general law om piracy is privateering. Finally the law of piracy provides procedures for the prosecutes pirates and for the alleged pirate to defend against those charges.

II. Law of Piracy and its sources.

Regarding the law defining piracy; Their are many laws on piracy however it is possible assemble a definition of piracy. An individual is guilty of piracy if he disposes and “carries away” or attempts to dispossess and carry away another’s vessel its cargo or passengers property on this said vessel; or be the commander or member of crew of a ship used as platform for the completed or attempted act of piracy. All the aforementioned conduct will unless the crew conducting the piratical act is acting under and according to a letter of marque or otherwise functioning as a state apparatus. Furthermore for one to be guilty of piracy the piratical act must take place in international waters which exists at least 3 miles from the coast of the mainland. The law banning piracy would not limit it self to people engaging in traditional acts of piracy; the law also classifies people knowingly helping or involving themselves with pirates as pirates themselves. The type of help or involvement classified as piracy include conspiring with the pirates, financing the pirates, procuring items to be used by pirates, holding stolen goods for them, advising them, directing from shore giving them equipment or helping them recruit etc.

The sources of these laws banning piracy varied. Like all law much of the laws banning piracy were customary law or international customary law. Customary law is created overtime based on a significant number of people or entities engaging in or not engaging an activity based on a belief of a legal duty or legal right. During the age of discovery and latter countries such as England began to use statues as a tool against piracy. These early statues such as the offenses at Sea act of 1535 and the Piracy act of 1698 stated that piracy was illegal and the procedure to be used in Piracy cases. However, in England, these statues did not completely overthrow the customary law regime. These statues such as the Piracy Acts of 1698, and 1717 usually did not generally define piracy and allowed the question of what activities constituted piracy to be

 

Read More